Fig. 5

TLS combined with TIL had high predictive accuracy for 5-year OS. ROC curves indicating the predictive accuracy, sensitivity and specificity of each potential parameter. The AUCs of TLS, CD8 and CD57 were 0.641 (95% CI 0.558–0.725), 0.682 (95% CI 0.599–0.765) and 0.656 (95% CI 0.571–0.741, respectively), but TLS combined with CD8+ T cells and CD57+ NK cells provided the highest predictive accuracy (AUC = 0.730; 95% CI, 0.654–0.805)