Fig. 7
From: Effect of the nano/microscale structure of biomaterial scaffolds on bone regeneration
MiR-222 in the scaffold enhance tissue regeneration. a SEM images of microspheres in the solution and hydrogel state. b TEM images of porous and spherical morphology of mesoporous silica nanoparticles (MSNs) and miR222/MSNs. c Micro-CT images of new bone formation after implantation of MSN, MSN/ASP, and miR222/MSN/ASP microsphere hydrogels in rat mandible defects for 10 w. d H&E and Masson’s trichrome staining of new bone formation in different groups. (Adapted with permission from the ref. 144 Copyright 2019, The Royal Society of Chemistry.)
