Fig. 6 | International Journal of Oral Science

Fig. 6

From: Copy number alteration profiling facilitates differential diagnosis between ossifying fibroma and fibrous dysplasia of the jaws

Fig. 6

The association between CNA and malignant transformation in Case 2. a–c H&E staining images showing the tissue morphology of Case 2 in 2009 (a), 2011 (b), and 2013 (c). Magnification: ×12.5 (upper panels) and ×200 (lower panels). d Normalized frequency distribution of CNAscore in Case 2 and in OS and OF samples. e CNA profiles of 37 samples in Case 2. Heatmap (upper panel) and aggregation of copy number alterations (lower panel) show the key CNA events for specific chromosomes. For the lower panel, the y axis represents the percentage of samples harboring CNAs. f CNA profiles of 11 samples from two osteosarcoma patients. Heatmap (upper panel) and aggregation of copy number alterations (lower panel) show the key CNA events for specific chromosomes. For the lower panel, the y axis represents the percentage of samples harboring CNAs.

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