Fig. 7 | International Journal of Oral Science

Fig. 7

From: Porphyromonas gingivalis exacerbates ulcerative colitis via Porphyromonas gingivalis peptidylarginine deiminase

Fig. 7

P. gingivalis and comΔppad exacerbate UC by downregulating IL-10 compared to Δppad as shown by immunofluorescence staining analysis. a Colon sections of mice from NC group, DSS group, P. gingivalis + DSS group, Δppad + DSS group, and comΔppad + DSS group were stained with anti-CD4 and anti-IL-10 antibodies. Scale bar: 50 μm. b The IL-10 intensity in the CD4+ T cells of mice was quantified (n = 6 in each group). The data are presented as the mean ± SD. *P < 0.05, **P < 0.01, ***P < 0.000 1 by independent 2-tailed Student’s t test and one-way ANOVA combined with Mann-Whitney U test

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