Fig. 3

ICF regulates the P53 and cell cycle pathways in iPSCs. RNA sequencing analysis of iPSCs treated with ICF and control was performed using the Kyoto Encyclopedia. Heat map illustrates differentially expressed genes in the P53 signaling pathway and cell cycle pathways (a, b). Graph represents the mRNA expression of selected genes (Ccnd1, Ccng1, and Cdk6) from RNA sequencing results (c–e). Bars indicate significant difference between conditions (**P < 0.01)