Fig. 1

The aetiology of TMJ-OA cartilage and subchondral bone c. a H&E staining of the condylar process. FC, fibrous cartilage; F, fibrous zone; P, proliferative zone; M, mature chondroblast zone; CC, calcification zone; H, hypertrophic layer. b TMJ-OA model rat sagittal sections were stained with H&E (top) and glycosaminoglycan (red) safranin O/Fast Green (bottom). Scale bars: 20 μm. c Representative μCT images showing subchondral bone of sham and TMJ-OA model rats. Scale bars: 300 μm. d FC/CC and e Mankin score in sham and TMJ-OA model rats. *P < 0.05, **P < 0.01. f–h Quantitative μCT data of sham and TMJ-OA rats. *P < 0.05, **P < 0.01. n = 8–10