Fig. 7 | International Journal of Oral Science

Fig. 7

From: Histone demethylase JMJD3 downregulation protects against aberrant force-induced osteoarthritis through epigenetic control of NR4A1

Fig. 7

Administration of GSK-J4 or si-JMJD3 nanocomplex effectively alleviates OA pathogenesis. a Histological analysis of tissue samples and corresponding OARSI scores in different groups. Scale bar: 100 μm (b) Immunohistochemistry staining of COLII, SOX9, COX-2, and MMP13 for evaluating cartilage pathogenesis in tissue samples from mice with different treatments. Scale bar: 50 μm *P < 0.05; **P < 0.01; ***P < 0.001

Back to article page