Fig. 1
From: Disrupted tenogenesis in masseter as a potential cause of micrognathia
Osr2-cre; Rosa26R-mT/mG mice showed the Osr2-cre pattern in the developing craniofacial region. a–d Cryostat sections of the E12.5 Osr2-cre; Rosa26R-mT/mG facial region. The white arrowheads in a–c indicated Cre activity (green fluorescence) in the presumptive masseter tendon. e–h Cryostat sections of the E13.5 Osr2-cre; Rosa26R-mT/mG facial region. The areas in the boxes of f–h were magnified in f’, g’ and h’, respectively. The white arrowheads in e indicated the Cre activity (green fluorescence) in the presumptive masseter tendon. i–l Cryostat sections of the E16.5 Osr2-cre; Rosa26R-mT/mG facial region. The white arrowheads in i indicated the Cre activity (green fluorescence) in the presumptive masseter tendon. The areas in the boxes of j–l were magnified in j’, k’ and l’, respectively. The white arrows in j’, k’ and l’ pointed to the forming tendons of masseter or mylohyoideus. The blue dotted lines circled mandibular bones, while the white dotted lines delineated masseter tendons; T tongue, Ins incisor, MC Meckel’s cartilage, Mb mandibular bone, Mr masseter region, Mas masseter myofibers, Mhs mylohyoideus myofibers, Ten tendon. Scale bars: 200 μm
