Fig. 1
From: Autologous mesenchymal stem cells offer a new paradigm for salivary gland regeneration

Epithelial-mesenchymal crosstalk during SG development. Studies of SG developmental morphogenesis have demonstrated a complex regulatory relationship between the maturing SG epithelium and the surrounding mesenchyme. The diagram shows signaling pathways that are common to both SG epithelium and mesenchyme and activated or inhibited during various phases of embryonic development. Adapted from previously published gene expression data by Jaskoll & Melnick227 and Suzuki et al.103 Created using BioRender.com