Table 3 Clinical trials evaluating the efficacy of MSCs for treating salivary gland damage

From: Autologous mesenchymal stem cells offer a new paradigm for salivary gland regeneration

Type of damage

MSC source

Transplant Type

NCT #

Trial phase

Country

Year

References

SS

BM

Allogeneic

NCT00953485

½

China

2009

229

SS

AD

Allogeneic

NCT04615455

2

Denmark

2020

 

IR

AD

Autologous

NCT02513238

2

Denmark

2015

216,237,238

IR

BM

Autologous

NCT03743155

2

Spain

2018

 

IR

AD

Allogeneic

NCT03874572

1

Denmark

2019

236

IR

AD

Autologous

NCT03876197

½

Denmark

2019

 

IR

BM

Autologous

NCT04007081

n/a

USA

2019

217

IR

AD

Allogeneic

NCT04776538

2

Denmark

2021

 
  1. Damage source: SS Sjogren’s Syndrome, IR irradiation (gamma radiation), MSC source: BM bone marrow, AD adipose tissue; NCT #: ClinicalTrials.gov identifier
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