Fig. 4 | International Journal of Oral Science

Fig. 4

From: Carcinoma-associated fibroblast-derived lysyl oxidase-rich extracellular vesicles mediate collagen crosslinking and promote epithelial-mesenchymal transition via p-FAK/p-paxillin/YAP signaling

Fig. 4

Regulation of αLOX by POSTN in CAF and their sEVs. a ELISA examination of POSTN in CAF-S1/S2/S3/S4 sEV (n = 3 per group). b Western blot analysis confirmed the downregulation of POSTN protein expression in CAF-S1/S2/S3/S4 induced by transfection with si-POSTN-1 or si-POSTN-2 compared with si-NC (n = 3 per group). c Quantitative analysis of POSTN and αLOX protein expression in CAF-S1/S2/S3/S4 sEV with POSTN downregulation (n = 3 per group). For blots source data, see Fig. S11. *P < 0.05, **P < 0.01, ***P < 0.001

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