Table 3 Prognostic factors for OSCC
From: Oral squamous cell carcinomas: state of the field and emerging directions
Prognostic factors | Indicators | Exhibitions | Outcomes |
|---|---|---|---|
Staging | Clinical stages: ▪ Stage I ▪ Stage II ▪ Stage III ▪ Stage IV | 5-year survival rate: ▪ 79.8% ▪ 70.0% ▪ 57.6% ▪ 53.9% | ▪ Poor prognosis |
Biomarkers | ▪ G3BP1 ▪ B7-H6 ▪ FAM3C | ▪ Upregulation | ▪ Poor prognosis |
Angiogenesis | ▪ MVD ▪ HMGA2 ▪ Id-1 | ▪ Upregulation | ▪ Poor prognosis |
HPV status | ▪ HPV+ ▪ p16+ | ▪ Upregulation | ▪ Favorable prognosis |
Tumor budding | ▪ Snail ▪ Twist | ▪ Upregulation | ▪ Poor prognosis |
Perineural invasion | ▪ miR-21/phosphatase ▪ Tensin homologs ▪ MMP-2 ▪ NGF ▪ Tyrosine kinase A | ▪ Upregulation | ▪ Poor prognosis |
