Fig. 2
From: MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1
MLL1 knock-downed SCAPs promoted functional recovery after SCI in rat model. a Spinal cord function was observed at 1, 2, 3, 4, and 5 weeks using the BBB scale to assess the limb motor function of rats. b The BBB scale showed that the SCAP/MLL1sh group gradually exhibited better spinal functional recovery at 4 to 5 weeks compared with that in the SCAP/Scramsh group. c Compared with those in the SCI and SCAP/Scramsh groups, the spinal cord morphology of the SCAP/MLL1sh group recovered well. Statistical significance was determined using one-way ANOVA, or the Kruskal–Wallis test. All error bars represent SD. (n = 6). *P ≤ 0.05. **P ≤ 0.01
