Fig. 4
From: MLL1 inhibits the neurogenic potential of SCAPs by interacting with WDR5 and repressing HES1

MLL1 binding with WDR5 in SCAPs. a MLL1 knock-down reduced the binding of MLL1 and WDR5 in SCAPs; b WDR5 knock-down reduced the binding of MLL1 and WDR5 in SCAPs; c WDR5 over-expression significantly increased the binding of MLL1 and WDR5 in SCAPs. Histone H3 served as an internal control. IgG was used as the negative control