Fig. 10 | International Journal of Oral Science

Fig. 10

From: Spatial transcriptomics reveals that metabolic characteristics define the tumor immunosuppression microenvironment via iCAF transformation in oral squamous cell carcinoma

Fig. 10

Validation of the OSCC hypermetabolic signature. a This heatmap displays the metabolic score of five pathways (glycolysis, pentose phosphate pathway, oxidative phosphorylation, glutamate/glutamine metabolism, and hypoxia) in OSCC samples from The Cancer Genome Atlas. Samples were divided into two clusters based on the median score of their metabolic signature. b The expression of Treg infiltration, CXCL12, HIF1A, and SLC16A1 was found to be upregulated in samples with high metabolic scores compared to those with low metabolic scores

Back to article page