Fig. 11 | International Journal of Oral Science

Fig. 11

From: A novel saliva-based miRNA profile to diagnose and predict oral cancer

Fig. 11The alt text for this image may have been generated using AI.

a Boxplots of risk probability scores were generated for healthy controls, patients with oral potentially malignant disorders (lichen planus, low grade and high-grade dysplasia) and oral cancer (stage I to IV). The saliva-based miRNA risk probability score effectively discriminates high-grade dysplasia from both Stage I oral cancer and controls. The risk score follows a gradual increase from mild dysplasia to the malignant stages except in Stage II and Stage IVB (Tukey’s HSD test, P ≤ 0.05). b Boxplots highlighting a higher risk probability score in patients with high-grade dysplasia who have developed oral cancer. It is evident that patients who have developed oral cancer have a relatively high-risk probability score compared to those who have not

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