Fig. 9
From: A novel saliva-based miRNA profile to diagnose and predict oral cancer
Localisation of miR-7-5p in FFPE tissue samples using miRNA in situ hybridisation. a1 H&E-stained Adjacent Normal Region of the test sample (x60), a2 Overview of H&E-stained section of the test sample (x10), a3 H&E-stained tumour region of test sample (x60). b1 miRNA in situ hybridisation of Adjacent Normal Region of the test sample (x60), b2 Overview of miRNA in situ hybridisation of test sample (x10), b3 miRNA in situ hybridisation of Tumour Region of Test sample (x60). It is evident that the tumour region exhibits stronger staining compared to the adjacent normal region, demonstrating the overexpression of miR-7-5p in the tumour region. c Negative control stained with DIG-labelled scrambled miRNA probe (x10). d Positive control using DIG-labelled U6 snRNA probe (x10)
