Table 1 Comparison of the characteristics and isolation rates of P. gingivalis between the two groups

From: Gingipain from Porphyromonas gingivalis causes insulin resistance by degrading insulin receptors through direct proteolytic effects

Characteristics

Control (n = 90)

Insulin resistance (n = 90)

P value

Demographics

Age/year

43.1 ± 6.2

44.9 ± 6.3

0.06a

SES (%)

  SES-1

23(25.6)

21(23.3)

 

  SES-2

27(30.0)

26(28.9)

 

  SES-3

18(20.0)

23(25.6)

 

  SES-4

6(6.7)

13(14.4)

 

  SES-5

16(17.7)

7(7.8)

0.15b

Educational attainment (%)

  High school and below

52(57.8)

38(42.2)

 

  Undergraduate

26(28.9)

34(37.8)

 

  Graduate and above

12(13.3)

18(20.0)

0.11b

Sex (%)

  Male

33 (36.7)

44 (48.9)

 

  Female

57 (63.3)

46 (51.1)

0.10b

Behaviours

  Smoking (%)

8 (8.9)

16 (17.8)

0.08b

  Alcohol consumption (%)

12 (13.3)

19 (21.1)

0.17b

Health related

  Body mass index

22.5 ± 3.6

23.6 ± 4.2

0.06a

  Chronic hypertension (%)

3 (3.3)

6 (6.7)

0.31b

Periodontal related

  Diagnosis of periodontitis (%)

31 (34.4)

48 (53.3)

0.01b

  Plaque index

1.9 ± 0.6

2.0 ± 0.4

0.19a

  Sites with BOP/%

31.4 ± 12.9

33.3 ± 14.4

0.35a

  PPD - Full mouth/mm

2.0 ± 0.6

2.1 ± 0.5

0.23a

  CAL - Full mouth/mm

1.8 ± 0.5

2.0 ± 0.4

0.004a

Insulin resistance related

  Fasting glucose/ (mmol/L)

4.86 ± 0.58

7.88 ± 1.60

< 0.001a

  Fasting insulin/ (µU/mL)

9.22 ± 2.39

13.64 ± 4.09

< 0.001a

  HOMA-IR

1.97 ± 0.49

4.65 ± 1.29

< 0.001a

Isolation of P. gingivalis

  Positive (%)

29 (32.2)

47 (52.2)

 

  Negative (%)

61 (67.8)

43 (47.8)

0.01b,c

  1. SES socioeconomic status, BOP bleeding on probing, PPD probing pocket depth, CAL clinical attachment loss; HOMA-IR homeostatic model assessment for insulin resistance
  2. at test
  3. bchi-squared test
  4. cthe crude relative risk of P. gingivalis positive isolation to negative isolation was 2.30 (95% CI = 1.26–4.21)