Fig. 3 | International Journal of Oral Science

Fig. 3

From: Cuproptosis-related lncRNA JPX regulates malignant cell behavior and epithelial-immune interaction in head and neck squamous cell carcinoma via miR-193b-3p/PLAU axis

Fig. 3

JPX regulates the malignant cell behaviors of CAL27 cells. a UMAP of epithelial cell populations in HC. b UMAP of epithelial cell populations in HNSCC. c Proportion plots of epithelial cell populations in HC and HNSCC. d UMAP plots comparing normal and malignant epithelial cells in HNSCC. e Expression of JPX is shown in UMAP of epithelial cell populations in HNSCC. f The relative expression levels of JPX in CAL27 cells with JPX knockdown or overexpression. g Live/dead staining of CAL27 cells with JPX knockdown or overexpression. Quantitative analysis of intensity is also shown. 20×, scale bar = 150 μm. h Ki-67 cells staining of CAL27 cells with JPX knockdown or overexpression. Quantitative analysis of intensity is also shown. 40×, scale bar = 50 μm. Con, control group; neg, empty vector group; pos, positive control group; L-, JPX knockdown group; V., vehicle group; L+, JPX overexpressed group. Wilcoxon signed-rank test: *P < 0.05, **P < 0.01, and ***P < 0.001

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