Fig. 5 | International Journal of Oral Science

Fig. 5

From: Single-cell sequencing systematically analyzed the mechanism of Emdogain on the restoration of delayed replantation periodontal membrane

Fig. 5

Effects of EMD on osteogenesis and osteoclast processes. a GO enrichment analysis chord diagram of Vtn+ fibroblasts, illustrating the relationship between GO terms and corresponding differentially expressed genes involved in various BP such as osteoblast differentiation, bone resorption, and cell adhesion. b ALP and ARS staining results of BMSCs. c Statistical map of expression of osteogenic genes by q-PCR. d The result of DMP1 immunofluorescence staining in rat sections. e UMAP plot showing the clustering of 3 915 cells into 5 distinct clusters. f Box plot comparing bone resorption activity between control and EMD-treated groups. g GO enrichment analysis chord diagram of osteoclasts, illustrating the relationship between gene ontology terms and corresponding differentially expressed genes involved in BP such as bone resorption, bone trabecula formation, and osteoblast differentiation. h Results of TRAP staining of rat sections. i Statistics of TRAP staining results

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