Fig. 10 | International Journal of Oral Science

Fig. 10

From: Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression

Fig. 10

Proteomics analysis showing Kdm1a knockout impairs STAT3 protein network: Global proteomics of tongue protein lysate from Kdm1a−/− + 4NQO compared to Kdm1afl/fl + 4NQO. a Volcano plot showing downregulation of STAT3 along with top dysregulated genes. b IPA analysis of candidate genes involved in EGFR-related network. c IPA analysis shows affected STAT3-associated events and well as increased tumor suppressor events

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