Fig. 13 | International Journal of Oral Science

Fig. 13

From: Lysine-specific demethylase 1 controls key OSCC preneoplasia inducer STAT3 through CDK7 phosphorylation during oncogenic progression and immunosuppression

Fig. 13

CDK7 is a key mediator of LSD1-induced STAT3 expression: RT-qPCR analysis to evaluate the effect of LSD1, STAT3, or CDK7 inhibitors on expression KDM1A, STAT3, and CDK7 expression in; a HSC3 cells, and b CAL27 cells. RT-qPCR analysis to evaluate the effect of genetic knockout of KDM1A, STAT3, or CDK7 on expression of KDM1A, STAT3, and CDK7 in; c HSC3 cells, and d CAL27 cells. “ns” P > 0.05, *P < 0.05, **P < 0.01, ***P < 0.001, ****P < 0.000 1

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