Fig. 2

Preparation and characterization of LR@PDH. a Changes of ROS levels in gingival crevicular fluid of health and periodontitis rats. b Survivals of LR after coating different concentration of PDH. c Sizes and d zeta potentials of LR, LR@PAH and LR@PDH. e SEM and f TEM images of LR and LR@PDH. g HAADF-STEM images of LR@PDH, and distribution of elements B, C, N, and O. h UV spectrum of LR, PDH, HA, LR@HA and LR@PDH. i Element B content in the supernatant of LR@PDH with treatment of PBS and H2O2. j CLSM images of LR@PDH (Cy5-labeled LR (red) coated with FITC-labeled PDH (green)). k Flow cytometry of LR and LR coated FITC-labeled PDH. ***P < 0.001 and ****P < 0.000 1. The data are presented as mean ± SD, n = 3