Fig. 2 | Journal of Exposure Science & Environmental Epidemiology

Fig. 2

From: Advancing internal exposure and physiologically-based toxicokinetic modeling for 21st-century risk assessments

Fig. 2

To evaluate a chemical-specific PBTK model for “chemical x” a, the predictions are compared to in vivo measured data for that chemical. For situations where chemical-specific TK data are not available b, generic TK models offer an alternative framework in which the model is parameterized and evaluated for all chemicals with in vivo data  and then extended for use with data poor chemicals

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