Table 3 Associations between changes in plasma levels of PFAS and changes in fasting glucose levels during 10 years of follow-up.

From: Associations between per- and polyfluoroalkyl substances (PFAS) and diabetes in two population-based cohort studies from Sweden

 

Adjusted

Adjusted also for BMI

Sex interaction

Women only

Men only

 

β

95% CI

p-value

β

95% CI

p-value

β

95% CI

p-value

β

95% CI

p-value

β

95% CI

p-value

PFOS

−0.003

−0.014, 0.009

0.60

−0.003

−0.01, 0.009

0.62

−0.004

−0.01, 0.004

0.28

−0.02

−0.04, −0.002

0.05

0.007

−0.009, 0.02

0.39

PFOA

−0.02

−0.04, −0.004

0.04

−0.02

−0.04, −0.004

0.046

−0.01

−0.02, −0.002

0.02

−0.03

−0.05, −0.01

0.02

−0.007

−0.03, 0.01

0.49

PFHxS

−0.008

−0.02, 0.004

0.22

−0.006

−0.02, 0.006

0.34

−0.006

−0.01, 0.002

0.12

−0.01

−0.03, 0.006

0.17

0.001

−0.02, 0.02

0.97

PFNA

−0.009

−0.02, 0.007

0.25

−0.009

−0.02, 0.005

0.23

−0.008

−0.02, 0.002

0.11

−0.02

−0.04, −0.0004

0.12

−0.005

−0.02, 0.01

0.66

PFDA

−0.01

−0.03, 0.006

0.12

−0.01

−0.03, 0.006

0.17

−0.008

−0.02, 0.002

0.11

−0.02

−0.04, −0.0004

0.14

−0.008

−0.03, 0.01

0.48

PFUnDA

−0.02

−0.04, −0.004

0.02

−0.02

−0.04, 0.004

0.047

−0.01

−0.02, −0.0002

0.02

−0.03

−0.05, −0.01

0.03

−0.008

−0.03, 0.02

0.52

  1. The fully adjusted model was adjusted for sex, participation time, BMI, insulin and diabetes medication, smoking, physical exercise and glomerular filtration rate (age was the same in all individuals). Significant p- values and associated results are marked in bold.
  2. β beta (regression coefficient), PFHxS perfluorohexane sulfonic acid, PFOS perfluorooctanesulfonic acid, PFOA perfluorooctanoic acid, PFNA perfluorononanoic acid, PFDA perfluorodecanoic acid, PFUnDA perfluoroundecanoic acid, SE standard error.