Fig. 4: Posterior predictions computed using the population toxicokinetic (TK) model in comparison to the experimental data. | Journal of Exposure Science & Environmental Epidemiology

Fig. 4: Posterior predictions computed using the population toxicokinetic (TK) model in comparison to the experimental data.

From: Derivation of human toxicokinetic parameters and internal threshold of toxicological concern for tenuazonic acid through a human intervention trial and hierarchical Bayesian population modeling

Fig. 4

The median and 90% confidence interval (CI) are represented by the black line and yellow ribbon, respectively. Each black circle represents an experimental data point. The posterior predictions are divided into four panels, one for each type of experimental data: concentration of tenuazonic acid (TeA) in blood (Ccpt), concentration of TeA and its phase-II metabolites in blood (Ccpt_tot), mass of TeA in urine (Qu), and mass of TeA and its phase-II metabolites in urine (Qu_tot).

Back to article page