Table 13 BIHS position: Management of hypertension associated with phaeochromocytoma/adrenergic crisis.

From: Management of hypertensive crisis: British and Irish Hypertension Society Position document

Hypertensive emergency state

Phaeochromocytoma/ adrenergic crisis

Speed of reduction and targets

Targets specific to the patient, BP, and specific presentation.

Medications

α blockade with oral phenoxybenzamine (if unavailable doxazosin can be used) followed by β blockade if necessary. IV Phentolamine may be used in a crisis if needed.

Phenoxybenzamine while preparing for surgery. β blockers are employed only if there’s persistence of tachycardia.

Benzodiazepines for illicit drug-induced hypertension such as cocaine and amphetamine induced.

Volume expansion with fluids and increased salt intake, as necessary to prevent postural hypotension and limit tachycardia.