Table 1 Study design and baseline characteristics of included Studies.

From: Effects of renal denervation on kidney function in patients with chronic kidney disease: a systematic review and meta-analysis

Author (Year)

Marin (2021) [32]

Scalise (2020) [31]

Ott (2019) [30]

Prasad (2019) [29]

Hameed (2017) [28]

Hering (2017) [27]

Hoye (2017) [22]

Kiuchi (2015) [26]

Ott (2015) [25]

Schlaich (2013) [24]

Hering (2012) [23]

Study Design

Single-arm Prospective

Prospective Comparative

Single-arm Prospective

Single-arm Prospective

Single-arm Prospective

Single-arm Prospective

Single-arm Prospective

Single-arm Prospective

Single-arm Prospective

Single-arm Prospective

Single-arm Prospective

Country

Italy

Italy

Germany

Canada

United Kingdom

Australia

New Zealand

Brazil

Germany

Australia, Europe, USA

Australia

CKD Stage

3,4,5

ESKD

ESKD

3,4

3,4

3,4,5

ESKD

2,3,4

3,4

ESKD

3,4

F/U (months)

12

12

6

24

6

24

12

24

12

12

6

Sample Size

21

12

6

25

11

46

9

30

27

9

15

Age

59.7 ± 17.1

56.5 ± 16.5

42.9 ± 27.9

62.8 ± 12.4

57.4 ± 14.4

66 ± 9

59 ± 9

55 ± 10

63.4 ± 9.4

47.4 ± 13.0a

61 ± 9

%Males (n)

85.7% (18)

66.7%

67% (4)

NR

72.7% (8)

61% (28)

89% (8)

43% (13)

81% (22)

NR

60% (9)

Number Anti-HTN Drugs

5.50 ± 0.90

4.80 ± 1.20

6.0 ± 0.47

4.9 ± 1.1

3.63 ± 0.84

4.9 ± 1.9

2.63 ± 2.62

4.6 ± 1.4

6.2 ± 1.1

4.20 ± 1.90

5.6 ± 1.3

% Diabetes (n)

61.9% (13)

33.3%

17% (1)

NR

45.5% (5)

48% (22)

22% (2)

37% (11)

56% (15)

NR

73% (11)

%CAD (n)

NR

NR

NR

NR

NR

28% (13)

NR

17% (5)

37% (10)

NR

NR

  1. Data for age and number anti-HTN drugs are displayed as means and standard deviation (SD).
  2. CKD Chronic Kidney Disease, ESKD End Stage Kidney Disease, F/U Follow-up, HTN Hypertension, NR Not Reported, NC Not Computable, CAD Coronary Artery Disease.
  3. aCombined mean age for both the RDN and control arm.