Table 3 Association between C2-quartiles and incidence of cardiovascular disease.

From: Impaired artery elasticity predicts cardiovascular morbidity and mortality- A longitudinal study in the Vara-Skövde Cohort

All (N = 2362, number of events = 108)

 

HR

95% CI for HR

p value

Crude data

2.68

2.12–3.39

<0.001*

Model 1

1.38

1.05–1.80

0.021*

Model 2

1.41

1.07–1.85

0.015*

Model 3

1.36

1.01–1.82

0.041*

Men (N = 1186, number of events = 70)

 

HR

95% CI for HR

p value

Crude data

2.94

2.17–3.99

<0.001*

Model 1

1.68

1.20–2.34

0.002*

Model 2

1.77

1.26–2.49

0.001*

Model 3

1.74

1.21–2.50

0.003*

Women (N = 1176, number of events = 38)

 

HR

95% CI for HR

p value

Crude data

2.34

1.62–3.37

<0.001*

Model 1

1.14

0.73–1.79

0.559

Model 2

1.14

0.72–1.78

0.581

Model 3

1.08

0.67–1.73

0.763

Women over 50 years of age (N = 338, number of events = 27)

 

HR

95% CI for HR

p value

Crude data

2.68

1.21–5.91

0.015*

Model 1

1.66

0.73–3.76

0.228

Model 2

1.64

0.72–3.71

0.239

Model 3

1.70

0.69–4.20

0.247

  1. Model 1: Adjusted for age, sex, heart rate, and SBP.
  2. Model 2: Adjusted as above and for HOMA- IR, LDL cholesterol, CRP.
  3. Model 3: Adjusted as above and for smoking, alcohol consumption and physical activity.
  4. p significance between C2 quartiles regarding CVD, SBP Systolic Blood Pressure, HOMA-IR Homeostatic Model Assessment for Insulin Resistance, LDL Low-Density Lipoprotein, DM Diabetes Mellitus, CRP C- reactive protein, C2 Small Artery Elasticity.
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