Table 5 Most common first- and second-line pharmacologic treatment of NAS, sample respondents in California Birth Hospitals in 2018.
From: Neonatal abstinence syndrome management in California birth hospitals: results of a statewide survey
Medication | Most common first-line medication (n = 59) | Most common second-line medication (n = 59) | ||||||
|---|---|---|---|---|---|---|---|---|
% | 95% CI | # of hospitals | % | 95% CI | # of hospitals | |||
Morphine (oral) | 73% | 60% | 83% | 43 | 12% | 6% | 23% | 7 |
Methadone | 27% | 17% | 40% | 16 | 24% | 15% | 36% | 14 |
Morphine (IV) | 10% | 4% | 21% | 6 | 14% | 7% | 25% | 8 |
Phenobarbital | 8% | 3% | 19% | 5 | 51% | 38% | 63% | 30 |
Clonidine | 7% | 2% | 17% | 4 | 32% | 22% | 45% | 19 |
Diazepam | 0% | 0% | 7% | 0 | 7% | 2% | 17% | 4 |
Tincture of opium (e.g., Laudanum, deodorized opium tincture) | 0% | 0% | 7% | 0 | 7% | 2% | 17% | 4 |
Buprenorphine | 0% | 0% | 7% | 0 | 5% | 1% | 14% | 3 |
Paregoric (e.g., camphorated tincture of opium) | 0% | 0% | 7% | 0 | 5% | 1% | 14% | 3 |
