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Is routine evaluation of gastric residuals for premature infants safe or effective?

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References

  1. Cobb BA, Carlo WA, Ambalavanan N. Gastric residuals and their relationship to necrotizing enterocolitis in very low birth weight infants. Pediatrics. 2004;113:50–3.

    Article  PubMed  Google Scholar 

  2. Bertino E, Giuliani F, Prandi G, Coscia A, Martano C, Fabris C. Necrotizing enterocolitis: risk factor analysis and role of gastric residuals in very low birth weight infants. J Pediatr Gastroenterol Nutr. 2009;48:437–42.

    Article  PubMed  Google Scholar 

  3. Farhath S, Aghai ZH, Nakhla T, Saslow J, He Z, Soundar S, et al. Pepsin, a reliable marker of gastric aspiration, is frequently detected in tracheal aspirates from premature ventilated neonates: relationship with feeding and methylxanthine therapy. J Pediatr Gastroenterol Nutr. 2006;43:336–41.

    Article  CAS  PubMed  Google Scholar 

  4. Li YF, Lin HC, Torrazza RM, Parker L, Talaga E, Neu J. Gastric residual evaluation in preterm neonates: a useful monitoring technique or a hinderance? Pediatr Neonatol. 2014;55:335–40.

    Article  PubMed  Google Scholar 

  5. Torrazza RM, Parker LA, Li Y, Talaga E, Shuster J, Neu J. The value of routine evaluation of gastric residuals in very low birth weight infants. J Perinatol. 2015;35:57–60.

    Article  CAS  PubMed  Google Scholar 

  6. Singh B, Rochow N, Chessell L, Wilson J, Cunningham K, Fusch C, et al. Gastric residual volume in feeding advancement in preterm infants (GRIP Study): a randomized trial. J Pediatr. 2018;200:79–83.

    Article  PubMed  Google Scholar 

  7. Kahan BC, Jairath V, Doré CJ, Morris TP. The risks and rewards of covariate adjustment in randomized trials: an assessment of 12 outcomes from 8 studies. Trials. 2014;15:139.

    Article  PubMed  PubMed Central  Google Scholar 

  8. Kahan BC, Morris TB. Reporting and analysis of trials using stratified randomisation in leading medical journals: review and reanalysis. BMJ. 2012;345:e5840.

    Article  PubMed  PubMed Central  Google Scholar 

  9. Altman DG (2005). Covariate imbalance, adjustment for. In: Armitage P, Colton T, editors. Encyclopedia of Biostatistics. 2nd ed. Chichester:John Wiley & Sons, Ltd; 2005, p. 1273–8.

  10. Raab GM, Day S, Sales J. How to select covariates to include in the analysis of a clinical trial. Control Clin Trials. 2000;21:330–42.

    Article  CAS  PubMed  Google Scholar 

  11. Hernández AV, Steyerberg EW, Habbema DF. Covariate adjustment in randomized controlled trials with dichotomous outcomes increases statistical power and reduces sample size requirements. J Clin Epidemiol. 2004;57:454–60.

    Article  PubMed  Google Scholar 

  12. Moher D, Hopewell S, Shulz KF, Montori V, Gøtzsche PC, Devereaux PJ, et al. CONSORT 2010 explanation and elaboration: updated guidelines for reporting parallel group randomised trials. BMJ. 2010;340:c869.

    Article  PubMed  PubMed Central  Google Scholar 

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Acknowledgements

The Journal Club is a collaboration between the American Academy of Pediatrics - Section of Neonatal Perinatal Medicine and the International Society for Evidence-Based Neonatology (EBNEO.org).

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Correspondence to Matthew A. Rysavy.

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Rysavy, M.A., Watkins, P.L., Colaizy, T.T. et al. Is routine evaluation of gastric residuals for premature infants safe or effective?. J Perinatol 40, 540–543 (2020). https://doi.org/10.1038/s41372-019-0582-8

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