Table 2 The effect of adverse events on expenditures.

From: Estimates of healthcare spending for preterm and low-birthweight infants in a commercially insured population: 2008–2016

Variable

Spending multiplier

95% confidence interval

Adverse events

 Bronchopulmonary dysplasia

2.15

(1.94, 2.38)

 Necrotizing enterocolitis

1.91

(1.65, 2.22)

 Respiratory distress syndrome

1.66

(1.58, 1.75)

 Retinopathy of prematurity

1.16

(1.07, 1.25)

 Neonatal sepsis

1.29

(1.22, 1.37)

Effect of sex

 Sex = Male

1.08

(1.03, 1.13)

Birthweight

 <500 g

1.43

(1.11, 1.85)

 500–749 g

2.81

(2.27, 3.48)

 750–999 g

2.25

(1.90, 2.67)

 1000–1249 g

2.04

(1.78, 2.34)

 1250–1499 g

1.90

(1.72, 2.11)

 1500–1749g

1.66

(1.54, 1.80)

 1750–1999g

1.34

(1.26, 1.43)

Gestational age in weeks

 <24

1.09

(0.84, 1.41)

 24

2.46

(1.90, 2.67)

 25–26

2.44

(2.00, 2.96)

 27–28

2.61

(2.23, 3.06)

 29–30

2.27

(2.02, 2.56)

 31–32

2.16

(2.00, 2.33)

 33–34

1.71

(1.62, 1.81)

  1. Multivariable analysis of the impact of adverse event occurrence on 6-month expenditures for infants with a documented birthweight and gestational age (n = 27,591) in the claims cohort. All spending multipliers had p values <0.001, with the exception of gestational age <24 weeks (p = 0.53) and birthweight <500 g (p = 0.012). The spending multipliers in this table represent the full model which contained all risk factors, gestational age, birthweight, and gender as variables.
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