Table 1 Observations made by the authors on admission cUS in newborn term infants presenting with encephalopathy.

From: Comment on ‘value of cranial ultrasound at initiation of therapeutic hypothermia for neonatal encephalopathy’

Ultrasound observation

Possible interpretation

Enlarged ventricles, sometimes with widening of the interhemispheric fissure and extracerebral space

Established antenatal insult

Porencephaly

Antenatal parenchymal haemorrhage suggestive of a coagulopathy or mutation of the COL4A1 gene

Germinolytic cysts, lenticulostriate vasculopathy and enlarged ventricles and a shallow Sylvian fissure

Peroxisomal disorder or cytomegalovirus

Diffuse echogenicity and/or anterior white matter cysts with early-onset seizures

Molybdenum cofactor deficiency or sulphite oxidase deficiency

Small vermis and pons

Pontocerebellar hypoplasia

Hypoplastic corpus callosum with and without an abnormal cerebellum

Non-ketotic hyperglycinaemia