Table 1 Sample characteristics and relationships to aEEG total Burdjalov score.

From: aEEG in the first 3 days after extremely preterm delivery relates to neurodevelopmental outcomes

Categorical variables (n = 64)

n

Percentage

p-valuea

Maternal factors

 Maternal marital status, married

27

42%

0.02

 Maternal prenatal smoking

13

20%

0.29

 Maternal prenatal use of alcohol

0

0%

b

 Maternal prenatal illicit drug use

4

6%

0.50

 Maternal education, Some college (n = 62)

28

45%

0.34

 Prenatal steroids

48

75%

0.41

 Delivery, Cesarean

37

58%

0.04

 Prenatal magnesium

37

58%

0.29

 Prenatal Indomethacin

0

0%

b

 Maternal spinal anesthesia

36

56%

0.49

 Maternal general anesthesia

13

20%

0.61

 No spinal or general anesthesia

15

23%

0.59

 Labor antibiotics

30

47%

0.41

Infant factors

 Race (African-American/Black)

34

53%

<0.01

 Insurance type, public (n = 46)

28

61%

0.66

 Infant sex, female

25

39%

0.84

 Cerebral injury (IVH grade III or IV or cystic PVL)

25

39%

0.04

 PDA (n = 63)

44

70%

0.90

 NEC (n = 61)

12

20%

0.32

 ROP (n = 61)

13

21%

0.55

 Expired

9

14%

0.69

Environment

 NICU room type, single patient room

30

47%

0.61

 Concurrent endotracheal intubation

45

70%

0.56

 Concurrent use of sedatives

24

38%

0.34

Continuous variables

Mean or median

Standard deviation or interquartile range

p-valuea

Maternal factors

 Maternal age, yrs

26.9

5.6

0.31

 Number of prenatal visits (n = 63)

4.1

2.3

0.46

Infant factors

 *EGA, wks

25.5

1.35

0.02

 Birth weight, grams

830.6

191.8

0.17

 Occipital-frontal circumference at birth, cm

23.2

1.7

0.81

 Apgar, 1 min

3.5

2.3

0.84

 Apgar, 5 min

5.8

1.8

0.59

 CRIB II score

11

(10–13)

0.29

 Cord gases (n = 40)

7.32

0.08

0.63

 Number of days on TPN, days

18

(11.25–33)

0.89

 Number of days on HFOV, days

0

(0–5)

0.34

 Number of days with endotracheal intubation, days

9

(1–34)

0.056

 Number of days on CPAP, days

13

(4–35)

0.23

 Number of days on nasal cannula, days

19

(7.5–30)

0.92

 Total oxygen hours, hrs

2256

(1380–2760)

0.85

 Total number of days on breast milk, days

40

(26–74)

0.91

 Length of stay, days

104

(76–126.5)

0.97

  1. IVH intraventricular hemorrhage, PDA patent ductus arteriosus (requiring Indomethacin or surgical ligation), NEC necrotizing enterocolitis (Bell’s stage IIb or higher), ROP retinopathy of prematurity (requiring surgery or Bevacizumab treatment), EGA estimated gestational age, CRIB-II Clinical Risk Index for Babies II, TPN total parenteral nutrition, HFOV high frequency oscillatory ventilation, CPAP continuous positive airway pressure.
  2. aP-value is from investigating the relationships of each factor with total Burdjalov cerebral maturation score, while controlling for EGA using linear regression analyses. Bolded values indicate significance (p < 0.05).
  3. bUnable to calculate due to variable being a constant.
  4. *The relationship between EGA and total Burdjalov cerebral maturation score was assessed using a univariate model.