Abstract
Shared decision-making in pediatrics can be problematic when disagreements arise. The impermissible-permissible-obligatory (I-P-O) framework helps define the limits of parental authority when clinicians disagree with parents. There is little guidance in the literature, however, on making critical clinical decisions when parents disagree with each other. We use a clinical case involving parental disagreement over resuscitation at borderline gestational age to provide context for an analysis of several potential approaches based on established ethical principles of pediatric decision-making. We identify four potential options for delivery room care: (1) Defer to the pregnant parent; (2) withhold resuscitation unless both parents agree to it; (3) attempt resuscitation if either parent requests it; (4) decide about resuscitation using a framework of advisability. The merits and flaws of each approach are discussed. We propose an expansion of the I-P-O framework that uses consideration of clinical details, an assessment of the patient’s best interest, and parental values to determine clinical advisability to guide decision-making in the setting of parental discordance.
This is a preview of subscription content, access via your institution
Access options
Subscribe to this journal
Receive 12 print issues and online access
$259.00 per year
only $21.58 per issue
Buy this article
- Purchase on SpringerLink
- Instant access to the full article PDF.
USD 39.95
Prices may be subject to local taxes which are calculated during checkout


Similar content being viewed by others
References
Cummings J. Antenatal counseling regarding resuscitation and intensive care before 25 weeks of gestation. Pediatrics. 2015;136:588–95. https://doi.org/10.1542/peds.2015-2336.
Mercurio MR, Cummings CL. Critical decision-making in neonatology and pediatrics: the I-P-O framework. J Perinatol. 2021;41:173–8. https://doi.org/10.1038/s41372-020-00841-6.
Cummings CL, Mercurio MR. Ethics of emerging technologies and their transition to accepted practice: intestinal transplant for short bowel syndrome. J Perinatol. 2012;32:752–6. https://doi.org/10.1038/jp.2012.69.
Mercurio MR. The ethics of newborn resuscitation. Semin Perinatol. 2009;33:354–63. https://doi.org/10.1053/j.semperi.2009.07.002.
Gillam L. Children’s bioethics and the zone of parental discretion. Monash Bioeth Rev. 2010;20:09.1–3.
Salter EK, Hester DM, Vinarcsik L, Matheny Antommaria AH, Bester J, Blustein J, et al. Pediatric decision making: consensus recommendations. Pediatrics. 2023;152. https://doi.org/10.1542/peds.2023-061832
Rysavy MA, Li L, Bell EF, Das A, Hintz SR, Stoll BJ, et al. Between-hospital variation in treatment and outcomes in extremely preterm infants. N. Engl J Med. 2015;372:1801–11. https://doi.org/10.1056/NEJMoa1410689.
Tyson JE, Parikh NA, Langer J, Green C, Higgins RD. Intensive care for extreme prematurity-moving beyond gestational age. N. Engl J Med. 2008;358:1672–81. https://doi.org/10.1056/NEJMoa073059.
Mercurio MR, Carter BS. Resuscitation policies for extremely preterm newborns: finally moving beyond gestational age. J Perinatol. 2020;40:1731–3. https://doi.org/10.1038/s41372-020-00843-4.
Maternal-fetal intervention and fetal care centers. Pediatrics. 2011;128:e473-8. https://doi.org/10.1542/peds.2011-1570
Perinatal Palliative Care: ACOG COMMITTEE OPINION, Number 786. Obstet Gynecol. 2019;134:e84–e89. https://doi.org/10.1097/aog.0000000000003425
Mercurio MR. The path more easily reversed: postponed withholding at borderline viability. Am J Bioeth. 2022;22:35–37. https://doi.org/10.1080/15265161.2022.2123985. Nov
Syltern J, Ursin L, Solberg B, Støen R. Postponed withholding: balanced decision-making at the margins of viability. Am J Bioeth. 2022;22:15–26. https://doi.org/10.1080/15265161.2021.1925777.
Anani U, Tucker Edmonds B, Andrews BL, Famuyide M, Feltman D. Default withdrawal: exacerbating mistrust for our most vulnerable families. Am J Bioeth. 2022;22:46–48. https://doi.org/10.1080/15265161.2022.2123980.
Janvier A, Barrington KJ. Delayed withholding: disguising withdrawal of life sustaining interventions in extremely preterm infants. Am J Bioeth. 2022;22:43–46. https://doi.org/10.1080/15265161.2022.2123986.
Hornik CP, Sherwood AL, Cotten CM, Laughon MM, Clark RH, Smith PB. Daily mortality of infants born at less than 30 weeks’ gestation. Early Hum Dev. 2016;96:27–30. https://doi.org/10.1016/j.earlhumdev.2016.03.003.
Meadow J, Arzu J, Rychlik K, Henner N. Trial of therapy on trial: inconsistent thresholds for discussing withdrawal of life-sustaining therapies in the neonatal intensive care unit. Am J Perinatol. 2024;41:e794–e802. https://doi.org/10.1055/a-1941-4285.
Kukora S, Laventhal N, Arnolds M. Postponed withholding: the wrong nudge. Am J Bioeth. 2022;22:66–69. https://doi.org/10.1080/15265161.2022.2123977.
Weise KL, Okun AL, Carter BS, Christian CW. Guidance on forgoing life-sustaining medical treatment. Pediatrics. 2017;140. https://doi.org/10.1542/peds.2017-1905
Textbook of neonatal resuscitation. In: Weiner GM, Zaichkin J, editors. 8th edition. ed. Itasca, IL:: American Academy of Pediatrics; 2021. p. 1 online resource (378 pages).
Mercurio MR. Physicians’ refusal to resuscitate at borderline gestational age. J Perinatol. 2005;25:685–9. https://doi.org/10.1038/sj.jp.7211395. Nov
Wilkinson D. The self-fulfilling prophecy in intensive care. Theor Med Bioeth. 2009;30:401–10. https://doi.org/10.1007/s11017-009-9120-6
Acknowledgements
Thank you to Dr. Hollie Baker for her review of the manuscript.
Author information
Authors and Affiliations
Contributions
AB participated in the initial concept, ethical analysis, and development of the framework proposed in this article. AB was primarily responsible for the initial draft of the manuscript. AB contributed to the drafting and revision of the manuscript. MM participated in the initial concept, ethical analysis, and development of the framework proposed in this article. MM contributed to the drafting and revision of the manuscript.
Corresponding author
Ethics declarations
Competing interests
The authors declare no competing interests.
Additional information
Publisher’s note Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Baker, A.C., Mercurio, M.R. Navigating parental disagreement: ethical analysis and a proposed approach. J Perinatol 45, 1017–1022 (2025). https://doi.org/10.1038/s41372-024-02152-6
Received:
Revised:
Accepted:
Published:
Version of record:
Issue date:
DOI: https://doi.org/10.1038/s41372-024-02152-6
