Table 2 Primary and secondary outcomes of babies in the two cohorts.
Control cohort (n = 253) | Probiotic cohort (n = 250) | p value | |
|---|---|---|---|
Primary outcomes | |||
Bloody stools | 45 (17.8%) | 12 (4.8%) | <0.0001 |
NEC > stage 2 | 12 (4.7%) | 1 (0.4%) | 0.003 |
Secondary outcomes | |||
DOL to full enteral feeds | 16.2 | 12.7 | <0.0001 |
Customized TPN days | 14.1 | 9.8 | <0.0001 |
NPO daysa | 1.2 | 0.8 | 0.27 |
Late antibiotic days | 2.2 | 1.3 | 0.09 |
Late onset sepsis | 8 (3.2%) | 9 (3.6%) | 0.37 |
UTIs | 7 (2.8) | 7 (2.8) | 0.42 |
Tracheitis | 11 (4.3%) | 5 (2%) | 0.14 |
Meningitis | 3 (1.2%) | 0 | 0.25 |
Duration of hospital stay, mean days | 48.3 | 47.1 | 0.59 |
CGA at discharge, mean weeks | 38.13 | 38.16 | 0.9 |
