Table 3 Patient characteristics by courses with and without ductus closure.
PDA Closed (n = 23) | PDA Not Closed (n = 113) | p value | |
|---|---|---|---|
GA at birth, weeks (median, IQR) | 25 [24–26] | 25 [24–26] | 0.83 |
Birth weight, grams (median, IQR) | 730 [612–855] | 710 [590–870] | 0.9 |
Female | 13 (57%) | 76 (67%) | 0.32 |
Cesarean delivery | 20 (87%) | 92 (81%) | 0.53 |
IUGR present | 8 (35%) | 33 (29%) | 0.59 |
Inborn delivery | 16 (70%) | 81 (72%) | 0.84 |
Race | |||
African American | 7 (30%) | 38 (34%) | 0.45 |
African American/White | 1 (4%) | 2 (2%) | |
Asian | 1 (4%) | 7 (6%) | |
Asian/White | 1 (4%) | 1 (1%) | |
Hispanic/Latin | 0 (0%) | 1 (1%) | |
Hispanic/Latino | 1 (4%) | 0 (0%) | |
Unknown | 1 (4%) | 6 (5%) | |
White | 11 (48%) | 58 (51%) | |
Apgar score (median, IQR) | |||
1 min | 2 [1–6] | 3 [1–6] | 0.84 |
5 min | 7 [5–7] | 6.5 [4.0–8.0] | 0.77 |
10 min | 7.0 [6.2–7.8] | 7.0 [6.0–7.0] | 0.71 |
Vasopressor requirementa, n | 4 (17%) | 7 (6%) | 0.073 |
VISMAX (median, IQR) | 5.5 [5-6.25] | 5 [5–10] | --- |
Respiratory support typea, n | --- | ||
Mechanical ventilation | 13 | 69 | |
CPAP | 10 | 42 | |
High flow nasal cannula | 0 | 2 | |
RSSMVa,b (median, IQR) | 3.7 [2.9–5.3] | 3.4 [2.7–5.0] | 0.42 |
RSSCPAPa,c (median, IQR) | 1.3 [1.1–1.4] | 1.4 [1.1–1.6] | 0.41 |
Intravenous Acetaminophen | 11/15 (73%) | 60/77 (78%) | 0.7 |
Enteral Acetaminophen | 8/15 (53%) | 25/77 (32%) | 0.12 |
Age at therapy start, days (median, IQR) | 12 [7.5–16.5] | 13 [8.0–19.0] | 0.58 |
Age < 14 days at starta | 13 (57%) | 60 (53%) | 0.76 |
