Table 3 Comparative analysis of adverse outcomes in neonates across groups.
From: Association of low shunt burden from PDA and adverse outcomes in premature infants
No PDA Burden (n = 69) | Low PDA Burden (n = 43) | p value | |
|---|---|---|---|
Primary outcome | |||
Death or adverse respiratory outcome | 33 (48) | 15 (35) | 0.239 |
Respiratory outcomes | |||
Grade 3 bronchopulmonary dysplasia | 2 (3) | 1 (2) | 1.000 |
Chronic pulmonary hypertension | 4 (6) | 0 (0) | 0.296 |
Pneumothorax | 2 (3) | 0 (0) | 0.523 |
Pulmonary hemorrhage | 2 (3) | 0 (0) | 0.523 |
Duration of intubation (days) | 17.5 [2, 38] | 7 [3, 21] | 0.152 |
Discharged on oxygen | 34 (49) | 19 (44) | 0.559 |
Neonatal outcomes | |||
Death | 0 (0) | 0 (0) | 1.000 |
IVH on day 7 | 13 (19) | 4 (9) | 0.278 |
Severe IVH (Grade 3 or 4) | 9 (13) | 0 (0) | 0.012 |
NEC stage 2 or greater | 3 (4) | 1 (2) | 1.000 |
Intestinal perforation | 1 (1) | 0 (0) | 1.000 |
Severe ROP requiring avastin treatment | 1 (1) | 0 (0) | 1.000 |
Systemic hypertension | 3 (4) | 0 (0) | 0.284 |
Length of stay (days) | 99.9 ± 61.8 | 82.6 ± 28.6 | 0.09 |
