Table 2 Best combined predictors of neonatal mortality in infants requiring therapeutic hypothermia, initial model.

From: Development of a prediction model for mortality in infants undergoing therapeutic hypothermia for neonatal encephalopathy

Variable

Coefficient (95% CI)

N (%)

OR (95% CI)

Mode of delivery

 Spontaneous vaginal delivery

-

88 (23.3)

Ref

 Prelabour Caesarean section

0.84 (-0.01, 1.68)

78 (20.63)

2.31 (0.99, 5.36)

Use of adrenaline

 No

-

320 (83.1)

Ref

 Yes

2.18 (1.38, 2.97)

65 (16.9)

8.81 (3.97, 19.57)

Base excess ≤ −22 mmol/L

 No

-

316 (83.60)

Ref

 Yes

1.62 (0.81, 2.44)

62 (16.4)

5.06 (2.25, 11.42)

Seizures on first day of life

 No

-

260 (68.78)

Ref

 Yes

1.18 (0.37, 2.97)

118 (31.22)

3.24 (1.45, 7.27)

 Constant

−4.03 (−4.83, −3.24)

 

0.02 (0.01, 0.04)

  1. The model included spontaneous vaginal, operative vaginal, prelabour Caesarean section, and Caesarean section after labour onset; only prelabour Caesarean section was statistically significant and retained.