Table 3 Best combined predictors of neonatal mortality in infants requiring therapeutic hypothermia, simplified model.

From: Development of a prediction model for mortality in infants undergoing therapeutic hypothermia for neonatal encephalopathy

Variable

Coefficient (95% CI)

N (%)

OR (95% CI)

Mode of delivery

 Spontaneous vaginal delivery

-

92 (23.9)

Ref

 Prelabour Caesarean section

0.86 (0.27, 1.69)

82 (21.3)

2.36 (1.03, 5.43)

Use of adrenaline

 No

-

320 (83.1)

Ref

 Yes

2.20 (1.41, 3.00)

65 (16.9)

9.04 (4.09, 20.01)

Base excess ≤ −22 mmol/L

 No

-

322 (83.6)

Ref

 Yes

1.67 (0.87, 2.48)

63 (16.4)

5.33 (2.38, 11.97)

Seizures on first day of life

 No

-

263 (68.3)

Ref

 Yes

1.19 (0.38, 1.99)

122 (31.7)

3.28 (1.47, 7.33)

 Constant

−4.01 (−4.89, −3.29)

 

0.02 (0.01, 0.04)

  1. The model included spontaneous vaginal, operative vaginal, prelabour Caesarean section, and Caesarean section after labour onset; only prelabour Caesarean section was statistically significant and retained.
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