Table 4 Association of severe acute kidney injury with patent ductus arteriosus.

From: Prolonged patent ductus arteriosus exposure and risk for late acute kidney injury in extremely preterm infants

 

No severe AKI

(n = 189)

Severe AKI

(n = 27)

Crude OR

(95% CI)

Adjusted ORa

(95% CI)

PDA duration

No PDA

133 (70)

19 (70)

REF

REF

Any PDA

56 (30)

8 (30)

1.0 (0.41–2.42)

0.71 (0.28–1.81)

4–7w

27 (14)

1 (4)

0.26 (0.03–2.02)

0.16 (0.02–1.32)

8–11w

14 (7)

1 (4)

0.50 (0.06–4.02)

0.53 (0.06–4.56)

≥12w

15 (8)

6 (22)

2.80 (0.97–8.10)

1.86 (0.59–5.91)

HPDA duration

No HPDA

145 (77)

20 (74)

REF

REF

Any HPDA

44 (23)

7 (26)

1.35 (0.55–3.29)

0.89 (0.35–2.28)

4–7w

24 (13)

1 (4)

NS

NS

8–11w

9 (5)

0 (0)

0.81 (0.10–6.70)

0.97 (0.11–8.88)

≥12w

11 (6)

6 (22)

3.96 (1.32–11.87)b

2.37 (0.72–7.78)

  1. aAdjusted for gestational age at birth.
  2. bp < 0.05.