Table 2 Respiratory outcomes in first 72 h after first extubation to CPAP.
RAM 5/6 | RAM 7/8 | BABI 5/6 | BABI 7/8 | ||
|---|---|---|---|---|---|
Pre-extubation Information | |||||
Number of Infants | n | 419 | 310 | 188 | 72 |
Gestational Age | weeks | 29.1 ± 2.5 | 28.4 ± 2.6* | 29.3 ± 2.4# | 28.8 ± 2.2 |
Birth Weight | grams | 1285 ± 439 | 1154 ± 440* | 1358 ± 447# | 1209 ± 460 |
DOL Extubation | day | 3.3 ± 4.8 | 5.4 ± 8.2 | 3.3 ± 6.6 | 4.7 ± 6.9 |
FiO2 4 h prior to extubation | % O2 | 27 ± 8 | 30 ± 9*& | 27 ± 9# | 30 ± 9*& |
Within the 72 h after extubation | |||||
Change FiO2 from Vent 4 h | % O2 | 3.1 ± 7.8 | 4.0 ± 7.6 | 2.7 ± 5.2 | 2.5 ± 8.1 |
Infants with >15% increase | # (%) | 28 (6.8%) | 17 (5.5%) | 7 (3.7%) | 2 (2.7%) |
FiO2 first 24 h | % O2 | 29 ± 11 | 32 ± 10*& | 28 ± 10# | 30 ± 9 |
FiO2/saturation ratio | 0.31 ± 0.12 | 0.34 ± 0.10* | 0.30 ± 0.11# | 0.32 ± 0.10# | |
Maximum CO2 value in 24 h | mmHg | 44 ± 10 | 45 ± 10 | 42 ± 10# | 45 ± 9 |
Infants with CO2 > 65 mmHg | # (%) | 10 (2.3%) | 7 (2.3%) | 6 (3.2%) | 1 (1.4%) |
Increased CPAP pressure | # (%) | 127 (30%) | 67 (22%)* | 63 (34%)# | 14 (19%) |
Apnea >6 in 24 h | # (%) | 50 (13%) | 39 (12%) | 8 (4%)*# | 6 (8%) |
CPAP Failure in 72 h | # (%) | 109 (26%) | 76 (25%) | 29 (15%)*# | 7 (10%)*# |