Table 2 Respiratory outcomes in first 72 h after first extubation to CPAP.

From: Comparison of nasal interfaces and pressures during critical time-points in NICU: observation data from over 10 years

  

RAM 5/6

RAM 7/8

BABI 5/6

BABI 7/8

Pre-extubation Information

Number of Infants

n

419

310

188

72

Gestational Age

weeks

29.1 ± 2.5

28.4 ± 2.6*

29.3 ± 2.4#

28.8 ± 2.2

Birth Weight

grams

1285 ± 439

1154 ± 440*

1358 ± 447#

1209 ± 460

DOL Extubation

day

3.3 ± 4.8

5.4 ± 8.2

3.3 ± 6.6

4.7 ± 6.9

FiO2 4 h prior to extubation

% O2

27 ± 8

30 ± 9*&

27 ± 9#

30 ± 9*&

Within the 72 h after extubation

Change FiO2 from Vent 4 h

% O2

3.1 ± 7.8

4.0 ± 7.6

2.7 ± 5.2

2.5 ± 8.1

Infants with >15% increase

# (%)

28 (6.8%)

17 (5.5%)

7 (3.7%)

2 (2.7%)

FiO2 first 24 h

% O2

29 ± 11

32 ± 10*&

28 ± 10#

30 ± 9

FiO2/saturation ratio

 

0.31 ± 0.12

0.34 ± 0.10*

0.30 ± 0.11#

0.32 ± 0.10#

Maximum CO2 value in 24 h

mmHg

44 ± 10

45 ± 10

42 ± 10#

45 ± 9

Infants with CO2 > 65 mmHg

# (%)

10 (2.3%)

7 (2.3%)

6 (3.2%)

1 (1.4%)

Increased CPAP pressure

# (%)

127 (30%)

67 (22%)*

63 (34%)#

14 (19%)

Apnea >6 in 24 h

# (%)

50 (13%)

39 (12%)

8 (4%)*#

6 (8%)

CPAP Failure in 72 h

# (%)

109 (26%)

76 (25%)

29 (15%)*#

7 (10%)*#

  1. Mean ± SD. * p < 0.05 vs RAM 5/6; #p < 0.05 vs RAM 7/8; & p < 0.05 vs Babi 5/6.