Fig. 1 | Laboratory Investigation

Fig. 1

From: Microvascular fractal dimension predicts prognosis and response to chemotherapy in glioblastoma: an automatic image analysis study

Fig. 1

The workflow for acquisition of tumor microvascular morphometric parameters. a IHC staining with anti-CD34 antibody. b Whole-slide digitalization. c Region selection (a portion of a representative image in order to show the vessel details). d Positive object extraction and measurement of MVD. e Image skeletonization. f Measurement of mvFD by box-counting algorithm

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