Fig. 4 | Laboratory Investigation

Fig. 4

From: Mast cells contribute to Enterovirus 71 infection-induced pulmonary edema in neonatal mice

Fig. 4

EV71 infection increased lung mast cells. To investigate the role of immune cells in the process of EV71 infection, the whole lung immune cells were analyzed by Flow Cytometry. a The proportion of lung immune cells from mock- (n = 4) and EV71-infected mice (n = 4). b The proportion of lung T cells with different phenotypes in mice with mock (n = 4) and EV71 infection (n = 4). c CD117 surface expression of mast cells. d The proportion of lung mast cells in mice with mock (n = 4) and EV71 infection (n = 4). e Expression of Foxp3 in lung T cells. f Mean fluorescence intensity (MFI) of Foxp3 in lung T cells of mice with mock (n = 7) and EV71 infection (n = 10). f FACs analysis of lung DCs. The data are expressed as means ± SEM. *P < 0.05, vs. Mock; **P < 0.01, vs. Mock; ***P < 0.001, vs. Mock

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