Fig. 4 | Laboratory Investigation

Fig. 4

From: An immunohistochemical approach to detect oncogenic CTNNB1 mutations in primary neoplastic tissues

Fig. 4

H&E and β-catenin immunohistochemical staining patterns in desmoid fibromatosis (ac), pilomatrixoma of skin (df), and solid pseudopapillary tumor of pancreas (gi). H&E stains on the left and positive β-catenin immunohistochemistry assays in the middle. These tumors are known to harbor altered/mutant β-catenin. Altered/mutant β-catenin fails to stain with the ABC (active β-catenin) antibody (right). Scale bars, 100 μm

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