Table 1 Kinexus summary profile results for changes in phosphor-protein expressions in hBMECs treated with p17 for 8 min
Target protein name | Phospho site (human) | Full target protein name | Z-ratio (P17 (1), Control) | Z-score difference (P17 (2)-Control) | Z-ratio (P17 (2), Control) | Z-score difference (SO75X-Control) | Z-ratio (SO75X, Control) |
|---|---|---|---|---|---|---|---|
MEK1 (MAP2K1) | T292 | MAPK/ERK protein-serine kinase 1 (MKK1) | 1.02 | −0.12 | −0.50 | 0.26 | 0.95 |
PLCg1 | Y771 | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-1 | 0.71 | 0.23 | 0.92 | 0.35 | 1.28 |
PLC R(PLCg2) | Y753 | 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma-2 | 0.44 | 0.10 | 0.39 | 0.31 | 1.10 |
EGFR | Y1172 | Epidermal growth factor receptor-tyrosine kinase | 0.34 | −0.15 | −0.61 | 0.30 | 1.07 |
Paxillin 1 | Y31 | Paxillin 1 | 0.34 | 0.31 | 1.26 | 0.15 | 0.53 |
p53 | S37 | Tumour suppressor protein p53 (antigenNY-CO-13) | 0.60 | 0.13 | 0.53 | 0.54 | 1.94 |
