Fig. 1
From: Protective effect and mechanism of IL-10 on renal ischemia–reperfusion injury
IL-10 increased following IRI. a Ischemia-induced upregulation of IL-10 levels in serum from C57BL/6 mice revealed by ELISA from 5 to 120 h after renal IRI compared to the sham-operated controls. b Upregulation of IL-10 mRNA expression in the kidney compared to the sham-operated controls. mRNA expression were measured by real-time PCR. The expression levels were normalized to the expression of 18S rRNA. The data are mean fold-increase ± SEM. Different treatments were compared by a one-way ANOVA followed by Dunnett’s test for individual comparisons between group means. *p < 0.05, ****p < 0.0001, C57BL/6 mice at 5 h after IRI (n = 6) vs. the sham-operated control mice (n = 5) and C57BL/6 mice at 24, 48, and 120 h after IRI (n = 6, n = 6, and n = 5)
