Fig. 3
From: Rapid diagnosis of IDH1-mutated gliomas by 2-HG detection with gas chromatography mass spectrometry
A compressed GC-MS method for rapid 2-HG detection. a Diagram showing the standard and compressed methods. b Metabolite profiling in IDH1-mutated glioma samples. Arrow pointing the 2-HG peak. When the vacuum-drying time is shortened to 8 min or the MTBSTFA reaction time is cut to 15 min, the 2-HG peak cannot be detected by GC-MS. c Comparison of metabolite profiles determined by the standard and compressed methods. The AUC of d 2-HG and e l-glutamic acid in IDH1-mutated glioma samples (n = 58) as determined by the standard and compressed GC-MS methods
