Fig. 3 | Laboratory Investigation

Fig. 3

From: Impaired mitophagy triggers NLRP3 inflammasome activation during the progression from nonalcoholic fatty liver to nonalcoholic steatohepatitis

Fig. 3

PA treatment resulted in impaired mitophagy in primary hepatocytes. Representative confocal micrographs of MitoTracker (red) and LC3B (green) coimmunofluorescent staining in primary hepatocytes treated with PA for different durations (indicated on the left). DAPI was used for nuclear staining (blue). Orange color represents the overlapping of MitoTracker with LC3B (merged panel). Images were taken at original magnification (×400). Scale bars = 7.5 μm

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