Table 1 Autopsy case demographics
Age at onset | Age at death | Pathology diagnosis | NFTs | Aβ plaques | Braak stage | Thal phase | CERAD score | |
|---|---|---|---|---|---|---|---|---|
MSA | ||||||||
Case 1 | 68 | 71 | SND/MSA-P | + | + | − | 2 | C1 |
Case 2 | 35 | 60 | SND/MSA-P | − | + | − | 1 | C0 |
Case 3 | 69 | 77 | SND/MSA-P/VaD | + | − | 2 | 0 | C0 |
Case 4 | 65 | 71 | OPCA/MSA-C | − | + | − | 3 | C1 |
Case 5 | 63 | 68 | SND/MSA-P | Rare | + | 1 | 3 | C2 |
Case 6 | 57 | 59 | OPCA/MSA-C | + | + | 3 | 2 | C2 |
DLB | ||||||||
Case 1 | 67 | 72 | DLB/AD | + | + | 5–6 | 3 | C2 |
Case 2 | 60 | 68 | DLB/AD/CAA | + | + | 6 | 5 | C3 |
Case 3 | 61 | 66 | DLB/AD/CAA | + | + | 4 | 3 | C3 |
Control | ||||||||
C1 | N/A | 78 | No neuropathology diagnosis | − | − | 1 | 0 | 0 |
C2 | N/A | 74 | No neuropathology diagnosis | − | − | 1 | 0 | 0 |
C3 | N/A | 77 | No neuropathology diagnosis | − | − | 2 | 0 | 0 |
C4 | N/A | 82 | Cerebrovascular arteriolosclerosis | − | − | 2 | 2 | 1 |
C5 | N/A | 52 | No neuropathology diagnosis | − | − | 2 | 2 | 1 |
